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Alvinotec-Irinotecan HCl

Drug Name : Alvinotec-Irinotecan HCl
Drug Category : AntineoPlastics
Pharmacological Category: آلکیله کننده ها / Alkylating agent
Brand Name : Alvinotec
Drug Forms :

IRINOTECAN Hydrochloride Injection is available in three 20 mg/mL single-dose sizes:


2 mL-fill vial containing 40 mg IRINOTECAN Hydrochloride
5 mL-fill vial containing 100 mg IRINOTECAN Hydrochloride
15 mL-fill vial containing 300 mg IRINOTECAN Hydrochloride


Overdose

There have been reports of overdosage at doses up to approximately twice the recommended therapeutic dose, which may be fatal. The most significant adverse reactions reported were severe neutropenia and severe diarrhea. There is no known antidote for overdosage of IRINOTECAN Hydrochloride Injection. Maximum supportive care should be instituted to prevent dehydration due to diarrhea and to treat any infectious complications. 

FDA Approval

Initial FDA Approval: 1996